ï»¿The new research would also mark the first time that HDL was measured in large populations, and this would further confuse the diet/heart-disease relationship. The hypothesis that HDL particles or the cholesterol in HDL protects against heart disease had first been proposed in 1951 by David Barr and Howard Eder of New York Hospital–Cornell Medical Center. It had been confirmed in a handful of small studies through the 1950s, and by Gofman in the last paper he published on lipoproteins and heart disease, as had the observation that when HDL was low triglycerides tended to be high, and vice versa, which suggested some underlying mechanism linking the two. Nonetheless, heart-disease researchers had paid little attention to HDL, as the NIH biostatistician Tavia Gordon later explained, because the idea of a “negative relation” between cholesterol and heart disease—high HDL cholesterol implies a low risk of heart disease—“simply ran against the grain.” “It was easy to believe that too much cholesterol in the blood could ‘overload’ the system and hence increase the risk of disease,” Gordon wrote, “but how could ‘too much’ of one part of the total cholesterol reduce the risk of disease? To admit that fact challenged the whole way of thinking about the problem.” Now HDL, too, would be measured in these populations.*44 Reviews on neemrana fort palaceBuy vasotec In The Safe Drugs Pharmacy. BEST PRICE GUARANTEE!Buy Celexa - no prescription!